Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MHNVNLLNQAGLENALESVGCLDIVEDLIEKMQEY------VLYHTETAE---RFAIDIFTVVNNYTKKVHAIFNVLENEDG-----ETNVKNVEFEVMHFTE 3HP6 Chain:A ((263-330)) --------------------------DVLEKLAPYHEIVENILHYRQLGKLQSTYIEGLLKVVRPATKKVHTIFNQALTQTGRLSSTEPNLQNI---------

General information: TITO was launched using: RESULT: Template: 3HP6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 57 -4004 -70.24 -74.14 target 2D structure prediction score : 0.26 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -70.24 2D Compatibility (Sec. Struct. Predict.) : 0.26 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.256

(partial model without unconserved sides chains): PDB file : Tito_3HP6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3HP6-query.scw PDB file : Tito_Scwrl_3HP6.pdb: