Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MISVLFVCLGNICRSPMAEAIFRDLAAKKGLEGKIKADSAGIGGWHIGNPPHEGTQEILRREGISFDGMLARQVSEQDLDDFDYIIAMDAENIGSL-RSMAGFKNTSHIKRLLDYVEDSDLADVPDPYY--TGNFEEVCQLIKTGCEQLLASIQKEKQL 1DG9 Chain:A ((7-157)) --SVLFVCLGNICRSPIAEAVFRKLVTDQNISDNWVIDSGAVSDWNVGRSPDPRAVSCLRNHGIN-TAHKARQVTKEDFVTFDYILCMDESNLRDLNRKSNQVKNCRAKIELLGSYDPQKQLIIEDPYYGNDADFETVYQQCVRCCRAFLEKVR-----

General information: TITO was launched using: RESULT: Template: 1DG9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 777 -91590 -117.88 -618.85 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.79 3D Compatibility (PKB) : -117.88 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.551

(partial model without unconserved sides chains): PDB file : Tito_1DG9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1DG9-query.scw PDB file : Tito_Scwrl_1DG9.pdb: