Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKVTMLGAGSWGTALALVLTDNGNE-------VCVWAHRAD-----LIHQINELHENKDYLPNVKLSTSIKGTTDMKEAVSDADVIIVAVPTKAIREVLRQAVPFITKKAVFVHVSKGIE--PDSLLRISEIM--EIELPSDVRKDIVVLSGPSHAEEVGLRHPTTVTASSKSMRAAEEVQDLFINHNFRVYTNPDIIGVEIGGALKNIIALAAGITDGLGYGDNAKAALITRGLAEIARLGTKMGGNPL---TFSGLTGVGDLIVTCTSVHSRNWRAGNLLGK-GYKLEDVLEEM--GMVVEGVRTTKAAYQLSKKYDV--KMPITEALHQVLFNGQKVETAVESLMARGKTHEMEDLVNTFENQVK 1X0X Chain:A ((9-347)) -KKVCIVGSGNWGSAIAKIVGGNAAQLAQFDPRVTMWVFEEDIGGKKLTEIINTQHENVKYLPGHKLPPNVVAVPDVVQAAEDADILIFVVPHQFIGKICDQLKGHLKANATGISLIKGVDEGPNGLKLISEVIGERLGIP------MSVLMGANIASEVADEKFCETTIGCKDPAQGQLLKELMQTPNFRITVVQEVDTVEICGALKNVVAVGAGFCDGLGFGDNTKAAVIRLGLMEMIAFAKLFCSGPVSSATFLESCGVADLITTCYG--GRNRKVAEAFARTGKSIEQLEKELLNGQKLQGPETARELYSILQHKGLVDKFPLFMAVYKVCYEGQPVGEFIHCL---------------------

General information: TITO was launched using: RESULT: Template: 1X0X.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1795 -10937 -6.09 -34.72 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain A : 0.77 3D Compatibility (PKB) : -6.09 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.525

(partial model without unconserved sides chains): PDB file : Tito_1X0X.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1X0X-query.scw PDB file : Tito_Scwrl_1X0X.pdb: