Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKSKFEASIDNLKEIEMNAYAYELIREIVLPDMLGQDYSSMMYWAGKHLARKFPLE---------SWEEFPAFFEEAGW----GT-LTNVSA-KKQELEFELEG-PIISNRLK--H---QKEPCFQLEAGFIAEQIQLMNDQIAESYEQVKKRADKVVLTVKWDMKDPV 2C0J Chain:B ((36-159)) ----------------------------------------VLEGMGFRVGQALGERLPRETLAFREELDVLKFLCKDLWVAVFQKQMDSLRTNHQGTYVLQDNSFPLLL----GLQYLEEAPKFLAFTCGLLRGALYT-LGIESVVTASVAAL-PVCKFQVVIPKS---

General information: TITO was launched using: RESULT: Template: 2C0J.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 328 957 2.92 9.66 target 2D structure prediction score : 0.73 Monomeric hydrophicity matching model chain B : 0.57 3D Compatibility (PKB) : 2.92 2D Compatibility (Sec. Struct. Predict.) : 0.73 1D Compatibility (Hydrophobicity) : 0.57 QMean score : 0.395

(partial model without unconserved sides chains): PDB file : Tito_2C0J.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2C0J-query.scw PDB file : Tito_Scwrl_2C0J.pdb: