Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMQEETFYSVRMRASMNGSHEDGGKHISGGERLIPFHEMKHTVNALLEKGLSHSRGKPDFMQIQFEEVHESIKTIQPLPVHTNEVSCPEEGQKLARLLLEKEGVSRDVIEKAYEQIPEWSDVRGAVLFDIHTGKRMDQTKEKGVRVSRMDWPDANFEKWALHSHVPAHSRIKEALALASKVSRHPAVVAELCWSDDPDYITGYVAGK-K-MGYQ--RITA--MKEYGTEEGCRVFFIDGS--NDVNTYIHDLEKQPILIEWEEDHDS 4XJY Chain:A ((34-116)) --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQLCVVGPTEYA-DGLLRGMVQANGRRVHAERRAVDNPDLGTLCNVIYLGVVDERERQQVFRSLAGHPVLSISER----

General information: TITO was launched using: RESULT: Template: 4XJY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 228 6899 30.26 104.53 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.60 3D Compatibility (PKB) : 30.26 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.248

(partial model without unconserved sides chains): PDB file : Tito_4XJY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4XJY-query.scw PDB file : Tito_Scwrl_4XJY.pdb: