Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAAKFEVGSVYTGKVTGLQAYGAFVALDEET--QGLVHISEVTHGFVKDINEHLSVGDEVQVKVLAVDEEKGKISLSIRATQAAPEKKESKPRKPKAAQVSEEASTPQGFNTLKDKLEEWIEMSNRKDLIKK 1YZ6 Chain:A ((10-104)) -----EEGEFVVATVKRIHNYGAFLELDEYPGKEAFMHISEVASTWVRNIRDYLKEGQKVVAKVIRVDPRKGHIDLSLR--RVTQQQRKAKLQEFKRAQKAE------------------------------

General information: TITO was launched using: RESULT: Template: 1YZ6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 379 -11561 -30.50 -124.31 target 2D structure prediction score : 0.48 Monomeric hydrophicity matching model chain A : 0.77 3D Compatibility (PKB) : -30.50 2D Compatibility (Sec. Struct. Predict.) : 0.48 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.571

(partial model without unconserved sides chains): PDB file : Tito_1YZ6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1YZ6-query.scw PDB file : Tito_Scwrl_1YZ6.pdb: