Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MYFVDRSKIEKTLGFFEHQLALFDS-QTDWQS-EIGELALQRIGHLLIECILDTGNDMID-GFIMRDPGSYDDIMDILVDEKVVTEKEGDELKKLIAYRKTLVQQYLLADSGELYRLIKAHQTALQDFPKRIRSYLETELGPVSAFK 1WWP Chain:A ((3-118)) ----------------EKALATLKELAFLEDPSPVERDAAIQRFEYTFEAFWKALQAYLREKEGL-EGASPKGVIRLAREVGLLRDEEARLALGMVDDRSLTVHTYNEPLARAIFRRLPDYARLMEQVLGRLR--------------

General information: TITO was launched using: RESULT: Template: 1WWP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 421 -8626 -20.49 -76.34 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -20.49 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.483

(partial model without unconserved sides chains): PDB file : Tito_1WWP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1WWP-query.scw PDB file : Tito_Scwrl_1WWP.pdb: