Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKEEKRSSTGFLVKQRAFLKLYMITMTEQERLYGLKLLEVLRSEFKEIGFKPNHTEVYRSLHELLDDGILKQIKVKKEGAKLQEVVLYQFKD--YEAAKLYKKQLKVELDRCKKLIEKALSDNF 3L7W Chain:A ((7-100)) ---------------ALLIEYLILAIVSKHDSYGYDISQT---IKLI--ASIKESTLYPILKKLEKAGYLSTYTQ---EHQGRRRKYYHLTDSGEKHLVYLTKEWSVYKMTIDGIVE-------

General information: TITO was launched using: RESULT: Template: 3L7W.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 321 -37407 -116.53 -406.59 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -116.53 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.614

(partial model without unconserved sides chains): PDB file : Tito_3L7W.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3L7W-query.scw PDB file : Tito_Scwrl_3L7W.pdb: