Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIHQHPESFPKHFLWGSASAAYQIEGAWNEDGKGPSVWDVFTK--IPGKTFKGTNGEIAVDHYHRFKEDVALMAEMGLKAYRFSVSWPRVFPKGKGE-INEAGLAFYDSLIDELLSHHIEPVLTLYHWDLPQALMDEY-GGF---ESRNIIEDFNHYCITLYKRFGDRVKYWVTLNEQNYNFNHGFI--TAMHPPGV-KDRKRFYEANHIAFLANAKAIESFREY--VPEGKIGPSFAYSPAYPLSSH-PEDILAFENAEEFTNNWWLDMYCWGTYPQIPFRCLEKQGWAPTIEAGDMDLLAKGKPDFVGVNYYQTITYERNPLDGVSEGKMNTTGQKGTNQETGIPGVFKTKKNPHLTTSNWDWTIDPIGLRIGLRRITSRY-QLPVFITENGLGEFDK-VEDGTVQDDYRIDYLRSHLEQCRQAISDGVDLIGYCSWSFTDLLSWLNGYQKRYGFVYVNRDEESTSDLKRLKKKSFYWYQDVIKTNGESL 1QOX Chain:A ((2-450)) -SIHM---FPSDFKWGVATAAYQIEGAYNEDGRGMSIWDTFAHTP--GKVKNGDNGNVACDSYHRVEEDVQLLKDLGVKVYRFSISWPRVLPQGTG-EVNRAGLDYYHRLVDELLANGIEPFCTLYHWDLPQALQD--QGGWGSR---ITIDAFAEYAELMFKELGGKIKQWITFNEPWCMAFLSNYLGV--HAPGNK-DLQLAIDVSHHLLVAHGRAVTLFRELGI--SGEIGIAPNTSWAVPYR-RTKEDMEACLRVNGWSGDWYLDPIYFGEYPKFMLDWYENLGYKPPIVDGDMELI-HQPIDFIGINYYTSSMNRYNP------------GEAGGMLSSEAIS------MGAPKTDIG-WEIYAEGLYDLLRYTADKYGNPTLYITENGACYNDGLSLDGRIHDQRRIDYLAMHLIQASRAIEDGINLKGYMEWSLMDNFEWAEGYGMRFGLVHVDYD----T-LVRTPKDSFYWYKGVISRGWLDL

General information: TITO was launched using: RESULT: Template: 1QOX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2657 -242880 -91.41 -559.63 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -91.41 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.497

(partial model without unconserved sides chains): PDB file : Tito_1QOX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1QOX-query.scw PDB file : Tito_Scwrl_1QOX.pdb: