Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGTVNITVSDGVRYAVADEGPNASEAVVCLHGFTGSKQSWT-FLDEMLPDSRLIKIDCLGHGETDAPLNGKRYSTTRQVSDLAEIFDQLKLHKVKLIGYSMGGRLAYSFAMTYPERVSALVLESTTPGLKTLGERRERIMRDRKLADFILRDGLEAFVAYWENIPLFSSQQRLAEDIRYRIRSGRLRNNKIGLANSLTGMGTGSQPSLWSRVEEIDVPVLLICGEWDEKFC-AIN-QEVHKMLPSSRIEIVPKAGHTVHVEQPRLFGKIVSEFLTSI 4CCY Chain:A ((36-293)) ----YVSTR-FGKTHIIASGPKDAPSLILLHGGLFSSAMWYPNIAAWSSQFRTYAVDIIGDKNKSIPSA-AMETRADFAEWMKDVFDSLGLETAHLAGLSLGGSHIVNFLLRAPERVERAVVISPAEAFISFHPDVYKYA-----AELTGARGAESYIK-WITGDSYD---LHPLLQRQIVAGVEWQDEQRSLKPTENGF---PYVFTDQELKSIQVPVLLMFGEHEAMYHQQMAFERASVLVPGIQAEIVKNAGHLLSLEQPEYVNQRVLSFLCG-

General information: TITO was launched using: RESULT: Template: 4CCY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1478 -55144 -37.31 -216.25 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -37.31 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.441

(partial model without unconserved sides chains): PDB file : Tito_4CCY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4CCY-query.scw PDB file : Tito_Scwrl_4CCY.pdb: