Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGKGDVLEAAPTTTAYHSLMDEYGYEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKKASDDYLNKFLPREIQVMKVLRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLGIAYLHSKSIVHRDLKLENLLLDKWENVKISDFGFAKMVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYACPEILRGLPYNPFLSDTWSMGVILYTLVVAHLPFDDTNLK--KLLRETQKEVTFPANHTISQECKNLILQMLRQ-ATKRATILDIIKDSWVLKFQPEQPTHEIRLLEAMCQLHNTTKQHQSLQITT 2YEX Chain:A ((8-269)) -----------------------DWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVD-CP-ENIKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNN-------------RERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNKPLK------------------------------

General information: TITO was launched using: RESULT: Template: 2YEX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -144741 for 2062 contacts (-70.2/contact) + 2D Compatibility (PS) -26938 + (NN) -5529 + (LL) 3996 1D Compatibility (HY) -16400 + (ID) 4250 Total energy: -193862.0 ( -94.02 by residue) QMean score : 0.394

(partial model without unconserved sides chains): PDB file : Tito_2YEX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2YEX-query.scw PDB file : Tito_Scwrl_2YEX.pdb: