Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRSISCSKEYAEDVRNLNIRPEQLDDFFGQKDLIQ---NLKVFINAAKTRTEALDHVLLHGPPGLGKTTLAQIISKELRVSFRATSGPLLNKAGDLAAVLTT------LNAKDVLFIDEIHRLNRSIEEVLYTAMEDFCLDLLVGEGPSTRTLRIDLPPFTLVGATTRL--GLLSAPLRDRFGIPLRLEFYSFEELVDIIKRGTKV-------FSAEIEEDAIQEIACRARGTPRIALRLLRRIRDFVEVKD--NKKITHKIADSALSKLGIDKMGLNKLDVDYLRFLFNTSGSVGIDTISIALSEDSGNIEETVEPYLVKISFVKRTPRGRVLTDQGKEYLSLQY 3PVS Chain:A ((14-243)) ------------QPLAARMRPENLAQYIGQQHLLAAGKPLPRAIEA-----GHLHSMILWGPPGTGKTTLAEVIARYANADVERISAVTSG-VKEIREAIERARQNRNAGRRTILFVDEVHRF------AFLPHIEDG--------------------TITFIGATTENPSFELNSALLSRAR-VYLLKSLSTEDIEQVLTQAMEDKTRGYGGQDIVLPDETRRAIAELVNGDARRALNTLEMMADMAEVDDSGKRVLKPELLTEIAGERSARKGDRFYDLISALHKSVRGSAPDAALYWYARIITAGGDPLYVARRCLAIASEDVGNADPRAMQVAIAAWDCFTR

General information: TITO was launched using: RESULT: Template: 3PVS.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -119415 for 1495 contacts (-79.9/contact) + 2D Compatibility (PS) -21540 + (NN) -2984 + (LL) 3012 1D Compatibility (HY) -8000 + (ID) 2700 Total energy: -151627.0 ( -101.42 by residue) QMean score : 0.433

(partial model without unconserved sides chains): PDB file : Tito_3PVS.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3PVS-query.scw PDB file : Tito_Scwrl_3PVS.pdb: