Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGTVNITVSDGVRYAVADEGPNASEAVVCLHGFTGSKQSWT-FLDEMLPDSRLIKIDCLGHGETDAPLNGKRYSTTRQVSDLAEIFDQLKLHKVKLIGYSMGGRLAYSFAMTYPERVSALVLESTTPGLKTLG-ERRERIMRDRKLADF-ILRD---GLEAFVAYWENIPLFSSQQ--RLAEDIRYRIRSGRLRNNKIGLANSLT--GM---GTGSQPSLWSRVEEIDVPVLLICGEWDEKFC-AINQEVHKMLPSSRIEIVPKAGHTVHVEQPRLFGKIVSEFLTSI 3G9X Chain:A ((18-292)) ---------LGERMHYVDVGPRDGTPVLFLHGNPTSSYLWRNIIPHVAPSHRCIAPDLIGMGKSDKPD--LDYFFDDHVRYLDAFIEALGLEEVVLVIHDWGSALGFHWAKRNPERVKGIACMEFIRPFPTWDEWPEFARETFQAFRTADVGRELIIDQNAFIEGALPKCVVRPLTEVEMDHYREPFLK-PVDREPLWRFPNELPIAGEPANIVALVEAYMNWLHQSPVPKLLFWGTPGVLIPPAEAARLAESLPNCKTVDIGPGLHYLQEDNPDLIGSEIARWLPA-

General information: TITO was launched using: RESULT: Template: 3G9X.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1390 -15971 -11.49 -61.19 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -11.49 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.407

(partial model without unconserved sides chains): PDB file : Tito_3G9X.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3G9X-query.scw PDB file : Tito_Scwrl_3G9X.pdb: