Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSGQMFKVEIVTRPANFEKLKQELGKIGVTSLTFSNVHGCGLQKAHTELYRGVKIES-NVYERLKIEIVVSKVPVDQVTETAKRVLKTGSPGDGKIFVYEISNTINIRTGEEGPEAL 2O66 Chain:A ((10-124)) -DSKFYKVEAIVRPWRIQQVSSALLKIGIRGVTVSDVRGFG---------------EDKFVAKVKMEIVVKKDQVESVINTIIEGARTGEIGDGKIFVLPVSDVIRVRTGERGEKA-

General information: TITO was launched using: RESULT: Template: 2O66.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 375 -22171 -59.12 -223.94 target 2D structure prediction score : 0.84 Monomeric hydrophicity matching model chain A : 0.81 3D Compatibility (PKB) : -59.12 2D Compatibility (Sec. Struct. Predict.) : 0.84 1D Compatibility (Hydrophobicity) : 0.81 QMean score : 0.538

(partial model without unconserved sides chains): PDB file : Tito_2O66.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2O66-query.scw PDB file : Tito_Scwrl_2O66.pdb: