Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQYDQGVDLWSVGCIMGELLN-GSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKISFKEQV-PMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSELPIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG 4AU8 Chain:A ((6-293)) -QKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRV---------PSSALREICLLKELK-HKNIVRLHDVLH---KLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIP-VR--SAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYK--PYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDF-------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 4AU8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -179804 for 2219 contacts (-81.0/contact) + 2D Compatibility (PS) -28703 + (NN) -17175 + (LL) 2420 1D Compatibility (HY) -25600 + (ID) 6450 Total energy: -255312.0 ( -115.06 by residue) QMean score : 0.582

(partial model without unconserved sides chains): PDB file : Tito_4AU8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4AU8-query.scw PDB file : Tito_Scwrl_4AU8.pdb: