Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEKVYVAGAIPEVGLKLLQ-EHFEVEMYEGKGLVDKDTLIKGVKNATALISLLSTNVDKDVIDAGKDLKIIANYGAGFNNIDIEYAREKSIDVTNTPKASTNATADLTIGLVLAVARRIVEGDQLSRTTGFDGWAPLFFRGREVSGKTIGIIGLGEIGSAVARRARAFDMDVLYTGPNRKEEKEREIGAKYVDLDTLLKNADFITINAAYNPKMHHLIDTEQFKMMKSTVYLINASRGPIVHEQALVQALKDNEIEGAALDVYEFEPDI-TDDLKSLNNVVLTPHIGNATFEARDMMSKIVANAAISAVQGEKPQFVVN 1WWK Chain:A ((4-307)) -MKVLVAAPLHEKAIQVLKDAGLEVIYEEY---PDEDRLVELVKDVEAIIVRSKPKVTRRVIESAPKLKVIARAGVGLDNIDVEAAKEKGIEVVNAPAASSRSVAELAVGLMFSVARKIAFADRKMREGVWAKK---EAMGIELEGKTIGIIGFGRIGYQVAKIANALGMNILLYDPYPNEERAKEVNGKFVDLETLLKESDVVTIHVPLVESTYHLINEERLKLMKKTAILINTSRGPVVDTNALVKALKEGWIAGAGLDVFEEEPLPKDHPLTKFDNVVLTPHIGASTVEAQERAGVEVAEKVVKILKG--------

General information: TITO was launched using: RESULT: Template: 1WWK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -187220 for 2555 contacts (-73.3/contact) + 2D Compatibility (PS) -33258 + (NN) -18733 + (LL) 1040 1D Compatibility (HY) -25600 + (ID) 6450 Total energy: -270221.0 ( -105.76 by residue) QMean score : 0.589

(partial model without unconserved sides chains): PDB file : Tito_1WWK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1WWK-query.scw PDB file : Tito_Scwrl_1WWK.pdb: