Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKRESYQAEMFNWCEALKDQIQKRGQLDQFEDQIDKMIEALEDDQTTEEDWYKQAAALYRDITESDDTSERRAYVPIGKHVLPKLPYKYSALEPYISRDIMILHHTKHHQSYVDGLNKA-ESELKKARATKNYDLIT-------HWERELAFHGAGHYLHSIFWFSMHPNGK--RRPTGALFQMIDLSFGSYSAFKEHFTQASKKVEGVGWAILVWAPRSGRLEILTAEKH------QLFSQWDVIPLLPLDVWEHAYYLQYKNDRASYVDHWWNVVDWREAEKRFEQAKEVVWKLY 1AR5 Chain:A ((1-201)) -----------------------------------------------------------------------------AVYTLPELPYDYSALEPYISGEIMELHHDKHHKAYVDGANTALD-KLAEARD-------KADFGAINKLEKDLAFNLAGHVNHSVFWKNMAPKGSAPERPTDELGAAIDEFFGSFDNMKAQFTAAATGIQGSGWASLVWDPLGKRINTLQFYDHQNNLPA------GSIPLLQLDMWEHAFYLQYKNVKGDYVKSWWNVVNWDDVALRFSEARVA-----

General information: TITO was launched using: RESULT: Template: 1AR5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 760 -20181 -26.55 -109.09 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -26.55 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.573

(partial model without unconserved sides chains): PDB file : Tito_1AR5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1AR5-query.scw PDB file : Tito_Scwrl_1AR5.pdb: