Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKP--YPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP 3NIZ Chain:A ((20-309)) MEKYQKLEKVGEGTYGVVYKAKDS-QGRIVALKRIR------GIPSTAIREISLLKELHHPNIVSLIDVIHSERCLTLVFEFMEKDLKKVLDENKTGLQDSQIKIYLYQLLRGVAHCHQHRILHRDLKPQNLLINSDGALKLADFGLARAFGIPVR---HEVVTLWYRAPDVLMGSKKYSTSVDIWSIGCIFAEMIT-GKPLFPGVTDDDQLPKIFSILGTPNPREWPQVQELPLWKQRTFQVF-EKKPWSSIIPGFCQEGIDLLSNMLCFDPNKRISARDAMNHPYFKDLDP-

General information: TITO was launched using: RESULT: Template: 3NIZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -151756 for 2188 contacts (-69.4/contact) + 2D Compatibility (PS) -29401 + (NN) -12364 + (LL) 64 1D Compatibility (HY) -35200 + (ID) 8200 Total energy: -236857.0 ( -108.25 by residue) QMean score : 0.539

(partial model without unconserved sides chains): PDB file : Tito_3NIZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3NIZ-query.scw PDB file : Tito_Scwrl_3NIZ.pdb: