Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYIVQDLMETDLYKLLKSQ-QLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS-----------NRPIFPGKH-------YLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELD-DLPKERLKELIFQETARFQPGVLEAP 3N9X Chain:A ((20-412)) ---------------------------------KNVHVPDNYIIKHLIGRGSYGYVYLAYDKNTEKNVAIKKVNRMFEDLIDCKRILREITILNRLKSDYIIRLYDLIIPDDLLKFDELYIVLEIADSDLKKLFKTPIFLTEEHIKTILYNLLLGENFIHESGIIHRDLKPANCLLNQDCSVKVCDFGLARTI------------HVVTRWYRAPELILLQENYTKSIDIWSTGCIFAELLNMLQSHINDPTNRFPLFPGSSCFPHEKSNRDQLNIIFNIIGTPTEDDLKNINKPEVIKYIKLFPHRKPINLKQKYPSISDDGINLLESMLKFNPNKRITIDQALDHPYLKDVRKKKLE---TKKIILPFDDWMVLSETQLRYIFLKEVQSFHPELVIPS

General information: TITO was launched using: RESULT: Template: 3N9X.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -232412 for 2573 contacts (-90.3/contact) + 2D Compatibility (PS) -34696 + (NN) -11480 + (LL) 1056 1D Compatibility (HY) -35200 + (ID) 6600 Total energy: -319332.0 ( -124.11 by residue) QMean score : 0.750

(partial model without unconserved sides chains): PDB file : Tito_3N9X.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3N9X-query.scw PDB file : Tito_Scwrl_3N9X.pdb: