Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEMMGMENIQQNQGLKQKDEQFVWHAMKGAHQAD-SLIAQKAEGAWVTDTDGRRYLDAMSGLWCVNIGYGRKELAEAAYEQLKELPYYPLTQ----SHAPAIQLAEKLNEWLGGDY-VIFFSNSGSEANETAFKIARQYHLQNGDHS-RYKFISRYRAYHGNTLGALSATGQAQRKYK-YEPLSQGFLHAAPPDIYRNPD--DADTLESANEIDRIMTWELSETIAGVIMEPIITG-GGILMPPDGYMKKVEDICRRHGALLICDEVICGFGRTGEPFGFMHYGVK--PDIITMAKGITSAYLPLSATAVKRDIFEAYQGEAPYDRFRHVNTFGGSPAACALALKNLQIMEDEQLIQRSRDLGAKLLGELQALREH-PAVGDVRGKGLLIGIELVKDKLTKEPADAAKVNQVVAACKEKGLIIGKNGDTVAGYNNVIQLAPPFCLTEEDLSFIVKTVKESFQTI----- 1DTY Chain:A ((1-429)) ----------MTTDDLAFDERHIWHPYTSMTSPLPVYPVVSAEGCELILSDGRRLVDGMSSWWAAIHGYNHPQLNAAMK-SQIDAM--SHVMFGEITHAPAIELCRKLVAMTPQPLECVFLADSGSVAVEVAMKMALQYWDAK-GE-ARDRFLTFRNGYHGDTFGAMSVCDPDNSMHSLWKGYLPENLFAPAPQSRMDGEWD-ERDMVGFARLMAAHRH----EIAAVIIEPIVQGAGGMRMYHPEWLKRIRKICDREGILLIADEIATGFGRTGKLFACEHAE--IAPDILCLGKALTGGTMTLSATLTTREVAETISDGEA-GCFMHGPTFMGNPLACAAANASLAILESGDWQQQVADIEVQLREQLAPARD-AEMVADVRVLGAIGVVETT-----HPV-N---MAALQKFFVEQGVWIRPF-------GKLIYLMPPYIILPQQLQRLTAAVNRAVQDETFFCQ

General information: TITO was launched using: RESULT: Template: 1DTY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2307 -255285 -110.66 -622.65 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -110.66 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.497

(partial model without unconserved sides chains): PDB file : Tito_1DTY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1DTY-query.scw PDB file : Tito_Scwrl_1DTY.pdb: