Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAVKKVVTHPAEVLETPAETVTV---FDKKLKKLLDDMYDTMLEMDGVGLAAPQIGILKRAAVVEIGDDR--------GRIDLVNPEILEKSGEQ-TGIEGCLSFPNVYGDVTRADYVKVRAFNRQGKPFILEARGFLARAVQHEMDHLDGVLFTSKISKYYTEDELADMEG 1Y6H Chain:A ((1-168)) -SVRKILRMGDPILRKISEPVTEDEIQTKEFKKLIRDMFDTMRHAEGVGLAAPQIGILKQIVVVGSEDNERYPGTPDVPERIILNPVITPLTKDTSGFWEGCLSVPGMRGYVERPNQIRMQWMDEKGNQFDETIDGYKAIVYQHECDHLQGILYVDRLKDTKLFGFNET---

General information: TITO was launched using: RESULT: Template: 1Y6H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 758 -61814 -81.55 -396.24 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : -81.55 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.408

(partial model without unconserved sides chains): PDB file : Tito_1Y6H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1Y6H-query.scw PDB file : Tito_Scwrl_1Y6H.pdb: