Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKRIALLPGDGIGPEVLESATDVLKSVAERFNHEFEFEYGLIGGAAIDEHHNPLPEETVAACK-NADAILLGAVGGPKWDQNPSELRPEKGLLSIRKQLDLFANLRPVKVFESLSDASPLKKEYIDNVDFVIVRELTGGLYFGQPSKRYVNTEGEQEAVDTLFYKRTEIERVIREGFKMAAAR-------------KGKVTSVDKANVLE-SSRLWREVAEDVA---QEFPDVKLEHMLVDNAAMQLIYAPNQFDVVVTENMFGDILSDEASMLTGSLGMLPSASLSSSGLHLFEPVHGSAPDIAGKGMANPFAAILSAAMLLRTSFGLEEEAKAVEDAVNKVLASG-KRTRDLARSEEFSSTQAITEEVKAAIMSENTISNV 3TY4 Chain:A ((9-364)) RRIVLGLIPADGIGKEVVPAARRLMENLPAKHKLKFDFIDLDAGWGTFERTGKALPERTVERLKTECNAALFGAVQSPTHKV----AGYSSPIVALRKKMGLYANVRPVKSLDGAK---------GKPVDLVIVRENTECLYVKEERMVQNT-PGKRVAEAIRRISEEASTKIGKMAFEIAKSRQKIRESGTYSIHKKPLVTIIHKSNVMSVTDGLFRESCRHAQSLDPSYASINVDEQIVDSMVYRLFREPECFDVVVAPNLYGDILSDGAASLIGSLGLVPSANVGD-NFVMSEPVHGSAPDIAGRGIANPVATFRSVALMLEF-MGHQDAAADIYTAVDKVLTEGKVLTPDLGGK---SGTNEITDAVLANI---------

General information: TITO was launched using: RESULT: Template: 3TY4.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1854 -19542 -10.54 -57.99 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.77 3D Compatibility (PKB) : -10.54 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.550

(partial model without unconserved sides chains): PDB file : Tito_3TY4.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3TY4-query.scw PDB file : Tito_Scwrl_3TY4.pdb: