Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAIVKATDQSFSAETSEGVVLADFWAPWCGPCKMIAPVLEELDQEMGDKLKIVKIDVDENQETAGKYGVMSIPTLLVLKDGEVVETSVGFKPKEALQELVNKHL 4AJ7 Chain:B ((17-104)) -------------EAGNKLVVIDFYATWCGPCKMIAPKLEELSQSMSD-VVFLKVDVDECEDIAQDNQIACMPTFLFMKNGQKLDSLSG-ANYDKLLELVEKN-

General information: TITO was launched using: RESULT: Template: 4AJ7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 352 -60444 -171.71 -686.86 target 2D structure prediction score : 0.80 Monomeric hydrophicity matching model chain B : 0.79 3D Compatibility (PKB) : -171.71 2D Compatibility (Sec. Struct. Predict.) : 0.80 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.752

(partial model without unconserved sides chains): PDB file : Tito_4AJ7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4AJ7-query.scw PDB file : Tito_Scwrl_4AJ7.pdb: