Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTHDLIEKSKKHLWLPFTQMKDYDENPLIIESGTGIKVKDINGKEYYDGFSSVWLNVHGHRKKELDDAIKKQLGK--IAHSTLLGMTNVPATQLAETLIDISPKKLTRVFYSDSGAEAMEIALKMAFQYWKNIGK-PEKQKFIAMKNGYHGDTIGAVSV-GSIELFHHVYGPLMFESYKAPIPYVY------RSESGDPDECRDQCLRELAQLLEEHHEEIAALSIESMVQGASGMIVMPEGYLAGVRELCTTYDVLMIVDEVATGFGRTGKMFACEHENVQ--PDLMAAGKGITGGYLPIAVTFATEDIYKAFYDDYENLKTFFHGHSYTGNQLGCAVALENLALFESENIVEQVAEKSKKLHFLLQDLHAL-PHVGDIRQLGFMCGAELVRSKETKEPYPADRRIGYKVSLKMRELGMLTRPLG-DVIAFLPPLASTAEELSEMVAIMKQAIHEVTSLED 1DTY Chain:A ((1-429)) MTTDDLAFDERHIWHPYTSMTS-PLPVYPVVSAEGCELILSDGRRLVDGMSSWWAAIHGYNHPQLNAAMK-SQIDAM-SHVMFGEITHAPAIELCRKLVAMTPQPLECVFLADSGSVAVEVAMKMALQYWDAK-GE-ARDRFLTFRNGYHGDTFGAMSVCDPDNSMHSLWKGYLPENLFAPAPQSRMDGEWD-------ERDMVGFARLMAAHRH----EIAAVIIEPIVQGAGGMRMYHPEWLKRIRKICDREGILLIADEIATGFGRTGKLFACEHAE--IAPDILCLGKALTGGTMTLSATLTTREVAETISDGEAG--CFMHGPTFMGNPLACAAANASLAILESGDWQQQVADIEVQLREQLAPARD-AEMVADVRVLGAIGVVETT-----HPV---N---MAALQKFFVEQGVWIRPF-GKLIYLMPPYIILPQQLQRLTAAVNRAVQDETFFCQ

General information: TITO was launched using: RESULT: Template: 1DTY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2317 -31278 -13.50 -75.37 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.77 3D Compatibility (PKB) : -13.50 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.426

(partial model without unconserved sides chains): PDB file : Tito_1DTY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1DTY-query.scw PDB file : Tito_Scwrl_1DTY.pdb: