Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGTVNITVSDGVRYAVADEGPN--ASEAVVCLHGFTGSKQSWT-FLDEMLPDSRLIKIDCLGHGETDAPLNGKRYSTTRQVSDLAEIFDQLKLHKVKLIGYSMGGRLAYSFAMTYPERVSALVLESTTPGLKTLGERRERIMRDRKLADFILRDGLEAFVAYWENIPLFSSQQRLAEDIRYRIRSGRLRNNKIGLANSLTGMGTGSQPSLWSRVEEIDVPVLLICGEWDEKFC-AINQEVHKMLPSSRIEIVPKAGHTVHVEQPRLFGKIVSEFLTSI 2XUA Chain:A ((8-264)) -------AVNGTELHYRIDGERHGNAPWIVLSNSLGTDLSMWAPQVAALSKHFRVLRYDTRGHGHSEAPK--GPYTIEQLTGDVLGLMDTLKIARANFCGLSMGGLTGVALAARHADRIERVALCNTAARIGSPEVWVPRAVKA--RTEGMHA-LADAVLPRWFTADYM---EREPVVL-AMIRDVFVHTDKEGYASNCEAI---DAADLRPEAPGIKVPALVISGTHDLAATPAQGRELAQAIAGARYVEL-DASHISNIERADAFTKTVVDFLTE-

General information: TITO was launched using: RESULT: Template: 2XUA.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1534 -1311 -0.85 -5.18 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -0.85 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.457

(partial model without unconserved sides chains): PDB file : Tito_2XUA.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2XUA-query.scw PDB file : Tito_Scwrl_2XUA.pdb: