Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVLLQS-SYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALP-----RQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLERCKENLDSHLPPSQNTSELNTA 2B9H Chain:A ((1-314)) MPKRIVYNISSDFQLKSLLGEGAYGVVCSATH-KPTGEIVAIKKIEPFD-KPLFALRTLREIKILKHFK---HENIITIFNIQRPDSFENFNEVYIIQELMQTDLHRVISTQ---MLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLARIID-----VEFVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIGTPHSDNDLRCIESPRAREYIKSLPMYPAAPLEKMFPRVNPKGIDLLQRMLVFDPAKRITAKEALEHPYLQTYHDPNDEPEGEPIPPSFFEFDHYK

General information: TITO was launched using: RESULT: Template: 2B9H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -164843 for 2273 contacts (-72.5/contact) + 2D Compatibility (PS) -30168 + (NN) -10599 + (LL) 896 1D Compatibility (HY) -30800 + (ID) 5300 Total energy: -240814.0 ( -105.95 by residue) QMean score : 0.677

(partial model without unconserved sides chains): PDB file : Tito_2B9H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2B9H-query.scw PDB file : Tito_Scwrl_2B9H.pdb: