Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFR--EGDVWICMELMDT-SLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVDSVAK-TIDAGCKPYMAPERINPELN-QKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKGTDVASFVKLILGD 4OBO Chain:A ((22-294)) ------------------------------------------------PAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVT-------EIKLEINMLKKYSHHRNIATYYGAFIKKSDDQLWLVMEFCGAGSITDLVKN--TKGNTLKEDWIAYISREILRGLAHLHIH-HVIHRDIKGQNVLLTENAEVKLVDFG-----------RNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDM-HPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRT

General information: TITO was launched using: RESULT: Template: 4OBO.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -124799 for 1945 contacts (-64.2/contact) + 2D Compatibility (PS) -26145 + (NN) -14276 + (LL) 3328 1D Compatibility (HY) -20000 + (ID) 4400 Total energy: -186292.0 ( -95.78 by residue) QMean score : 0.492

(partial model without unconserved sides chains): PDB file : Tito_4OBO.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4OBO-query.scw PDB file : Tito_Scwrl_4OBO.pdb: