Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ------------------------MNGIAWMIVFCEIAFWVVIVLG-----LAVRYVFKRHTLGLLFLALTPVIDLILLAA--------------------TGVDLYRGASATAAH-------GIAAVYIGISIAYGKQMIQWADEK-FQYYV-TKKGTKPLKRFGMDHAKHGAKGWLRH---VLAYLIGAG-LLAGMIYFINDSSRTEALSGILKLWTVIIGIDFLITA-------SYFIWPKKEKASANLRS-------------------------------- 3QK7 Chain:A ((5-284)) RTDAIALAYPSRPRVLNNSTFLEMISWIGIELGKRGLDLLLIPDEPGEKYQSLIHLVETRRVDALIVAHTQPEDFRLQYLQKQNFPFLALGRSHLPKPYAWFDFDNHAGASLAVKRLLELGHQRIAFVSTDARISYVDQRLQGYVQTMSEAGLMPLAGYLQKADPTRPGGYLAASRLLALEVPPTAIITDCNMLGDGVASALDKAGLLGGEG------ISLIAYDGLPDDSLLDIAVTPIVQNTRTSVGKQIASMICDLLGGKDPKELQVLWQPEIGEGETDGVNR

General information: TITO was launched using: RESULT: Template: 3QK7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 749 -117260 -156.55 -655.08 target 2D structure prediction score : 0.40 Monomeric hydrophicity matching model chain A : 0.59 3D Compatibility (PKB) : -156.55 2D Compatibility (Sec. Struct. Predict.) : 0.40 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.243

(partial model without unconserved sides chains): PDB file : Tito_3QK7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3QK7-query.scw PDB file : Tito_Scwrl_3QK7.pdb: