Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKLVPRFRKQWFAYLTVLCLALAAAVSFGVPAKAAENPQTSVSNTGKEADATKNQTSKADQVSAPYEGTGKTSKSLYGGQTELEKNIQTLQPSSIIGTDERTRISSTTSFPYRATVQLSIKYPNTSSTYGCTGFLVNPNTVVTAGHCVYSQD-HGWASTITAAPGRNGSSYPYGTYSGTMFYSVKGWTESKDTNYDYGAIKLNGSPG--NTVGWYGYRTTNSSSPVGLSSSVTGFPCDKTFGT----MWSDTKPIRSAETYKLTYTTDTYGCQSGSPVYRNYSDTGQTAIAIHTNGGSSYNLG-TRVTNDVFNNIQYWANQ 1P3C Chain:A ((1-211)) ---------------------------------------------------------------------------------------------VVIGDDGRTKVANTRVAPYNSIAYITF------GGSSCTGTLIAPNKILTNGHCVYNTASRSYSAKGSVYPGMNDSTAVNGSANMTEFYVPSGYINTGASQYDFAVIKTDTNIGNTVGYRSIRQVT----NLTGTTIKISGYPGDKMRSTGKVSQWEMSGSVTREDTNLAYYTIDTFSGNSGSAMLDQN----QQIVGVHNAG---YSNGTINGGPKATAAFVEFINY

General information: TITO was launched using: RESULT: Template: 1P3C.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1235 -68224 -55.24 -336.08 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -55.24 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.207

(partial model without unconserved sides chains): PDB file : Tito_1P3C.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1P3C-query.scw PDB file : Tito_Scwrl_1P3C.pdb: