Modeling by threading (Tito software)
Unconserved sides chains calculation (Scwrl software)
Evaluation (QMean software)
Input alignment information:
| Query sequence | MCDLIEPQPAEKIGKMKKLRRTLSESFSRIALKKDDTTFDEICVTKMSTRNCQGMDSVIKPLDTIPEDKKVRVQRTQSTFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSK--VNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHDII--HTKETLTLVFEYVHTDLCQYMDKH----PGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLI----SDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDI----QDQLERIFLVLGTPNEDTWPGVHSLPHFKPERF----TLYSSKNLRQAWNKLS--YVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESMRAFGKNNSYGKSLSNSKH |
| 4F6U Chain:A ((27-341)) | ------------------------------------------------------------------------------------------------------------------------------------------CKVGRGTYGHVYKAKRKDGKDDKDYALKQIE---GTGISMSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASK-VQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGF--------------VVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQE-NPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFL-------------------------- |
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General information:
TITO was launched using:
| RESULT:
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Template: 4F6U.pdb
Alignment : align.pir
Tito was launched with SMD and SCWRL
Tito text output
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3D Compatibility (PKB) -141899 for 1980 contacts (-71.7/contact) +
2D Compatibility (PS) -28630 + (NN) -12306 + (LL) 9900
1D Compatibility (HY) -26800 + (ID) 4950
Total energy: -204685.0 ( -103.38 by residue)
QMean score : 0.483
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