Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNTSNRRMGLFYVITGATCWGIGGTVAKKLFQEYQIDVNWLVTTRLLTAGMLLLMLQLFRKDRSQVIEVWKHKASAGQLLIFGLLGMLAVQYTYMASIQHGNAAVATLLQYLSPVIVIIYTLLRKQTVLTKQDIITVVLALVGCFFLLTNGSMSQLSVPAAAVVWGVLSGFAAAFYTLYAVGLLNKFDSLVVVGWAMIIGGFALGFIHPPWQLDFQRLTAEAYAYILFVILFGTMIAFWFFIKSLESLSPKETSLLGSLEPLSAVVTTVVWLKAPFGSFQWIGAICIIGITLILALHKEPSMESEKSILKIRNHANRDI 5AZB Chain:A ((261-286)) -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ISMGQILSIPMIVAGVIMMVWAYRRS------------------

General information: TITO was launched using: RESULT: Template: 5AZB.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 6 -895 -149.08 -34.40 target 2D structure prediction score : 0.81 Monomeric hydrophicity matching model chain A : 0.40 3D Compatibility (PKB) : -149.08 2D Compatibility (Sec. Struct. Predict.) : 0.81 1D Compatibility (Hydrophobicity) : 0.40 QMean score : 0.255

(partial model without unconserved sides chains): PDB file : Tito_5AZB.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5AZB-query.scw PDB file : Tito_Scwrl_5AZB.pdb: