Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNTLTVKDIKDRLQEVKDAQDPFIAQCENDPRKSVQTLVEQWLKKQAKEKALKEQWVNMTSYERLARNKGFRLIAGVDEVGRGPLAGPVVASAVILPEECEI--LGLTDSKKLSEKKREEYYELIMK----EALAVGIGIVE----ATVIDEINIYEASKMAMVKAIQDLS--DTPDYLLVDAMTLPLDTAQASII----KGDAKSVSIAAGACIAKVTRDRMMSAYAETYPMYGFEKNKGYGTKEHLEALAAYGPTELHRKTFAPVQSFR 1I3A Chain:A ((21-201)) ------------------------------------------------------------------------MKAGIDEAGKGCVIGPLVVAGVACSDEDRLRKLGVKDSKKLSQGRREELAEEIRKICRTEVLKVSPENLDERMAAKTINEI-LKECYAEIILRLKPEIAYVDSPD-VIPERLSRELEEITGLRVVAEHKADEKYPLVAAASIIAKVEREREIERLKEKFGDFGSGYASDPRTREVLKEWIASG----------------

General information: TITO was launched using: RESULT: Template: 1I3A.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 746 -50292 -67.42 -304.80 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -67.42 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.375

(partial model without unconserved sides chains): PDB file : Tito_1I3A.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1I3A-query.scw PDB file : Tito_Scwrl_1I3A.pdb: