Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEKYHGLEKIGEGTYGVVYKAQNN-YGETFALKKIRLEKEDEGIPSTTIREISILKELKHSNIVKLYDVIHTKKRLVLVFEHLDQDLKKLLDVCE-GGLESVTAKSFLLQLLNGIAYCHDRRVLHRDLKPQNLLINREGELKIADFGLARAFGIPVRKYTHEVVTLWYRAPDVLMGSKKYSTTIDIWSVGCIFAEMVNGTPLFPGVSEADQLMRIFRILGTPNSKNWPNVTELPKYDPNFTVYEPLPWESFLKGLDESGIDLLSKMLKLDPNQRITAKQALEHAYFKENN 3PXQ Chain:A ((9-296)) MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQD--

General information: TITO was launched using: RESULT: Template: 3PXQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -164454 for 2216 contacts (-74.2/contact) + 2D Compatibility (PS) -30016 + (NN) -11751 + (LL) 288 1D Compatibility (HY) -36000 + (ID) 9000 Total energy: -250933.0 ( -113.24 by residue) QMean score : 0.504

(partial model without unconserved sides chains): PDB file : Tito_3PXQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3PXQ-query.scw PDB file : Tito_Scwrl_3PXQ.pdb: