Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MCSGNQTSQNQTASTDFTLTGLFAESKHAALLYTVTFLLFLMALTGNALLILLIHSEPRLHTPMYFFISQLALMDLMYLCVTVPKMLVGQVTGDDTISPSGCGIQMFFHLTLAGA-EVFLLAAMAYDRYAAVCRPL-HYPLLMNQRVCQLLVSACWVLGMVDGLLLTPITMSFPFCQSRKILSFFCETPALLKLSCS--------DVSLYKMLTYLCCILMLLTPIMVISSSYTLILHLIH----RMNSAAGRRKALATCSSHMIIVLLLF--------GASFYTYMLRSSYHTAEQDMMVSAFYTIFTPVLNPLIYSLRNKDVTRALRSMMQSRMNQEK 1HZX Chain:A ((35-313)) -----------------------AEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFF-ATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAI--MGVAFTWVMALA--------------CAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYM-FVVHFIIPLIVIFFCYGQLVFTVKEAAA-----ATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGS-DFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNPLG

General information: TITO was launched using: RESULT: Template: 1HZX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -235017 for 1998 contacts (-117.6/contact) + 2D Compatibility (PS) -25487 + (NN) -3926 + (LL) 2444 1D Compatibility (HY) -5600 + (ID) 800 Total energy: -268386.0 ( -134.33 by residue) QMean score : 0.211

(partial model without unconserved sides chains): PDB file : Tito_1HZX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1HZX-query.scw PDB file : Tito_Scwrl_1HZX.pdb: