Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDEQSQGMQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIE--DNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDVTYVYDVAKRMHACTASS 2XKF Chain:A ((7-262)) --------------------------------DYEVLYTIGTG---RCQKIRRKSDGKILVWKELDYGSMTEAEKQM-LVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRVMTQLTLALKECHRRS---RDLKPANVFLDGKQNVKLGDF---------------FVGTPYYMSPEQMNR-SYNEKSDIWSLGCLLYELCALMPPFTA--FSQKELAGKIREGKFRRIPY-RYSDELNEIITRMLNLKDYHRPSVEEILENPLILEHHHHHH

General information: TITO was launched using: RESULT: Template: 2XKF.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -131085 for 1654 contacts (-79.3/contact) + 2D Compatibility (PS) -24732 + (NN) -16856 + (LL) 2280 1D Compatibility (HY) -22400 + (ID) 4400 Total energy: -197193.0 ( -119.22 by residue) QMean score : 0.577

(partial model without unconserved sides chains): PDB file : Tito_2XKF.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2XKF-query.scw PDB file : Tito_Scwrl_2XKF.pdb: