Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNVSVNIKNVTKEYRIYRTNKERMKDALIPKHKNKTFFALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKV-----------DRNGEVSVIAISAGLSGQLTGIENIEFKMLCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQKCLDKIYEFKEQ-NKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDVLPKYEAFLNDFKKKSKAEQKEFRNKLDEARFVIK 2YYZ Chain:A ((18-221)) --------------------------------------AVDGVSFEVKDGEFVALLGPSGCGKTTTLLMLAGIYKPTSGEIYFDDVLVNDIPPKYREVGMVFQNYALYPHMTVFENIAFPLRARRISKDEVEKRVVEIARKLLIDNLLDRKPTQLSGGQQQRVALARALVKQPKVLLFDEPLSNLDANLRMIMRAEIKHLQQELGITSVYVTHDQAEAMTMASRIAVFNQGKLVQYGTPDEV----------------------------------

General information: TITO was launched using: RESULT: Template: 2YYZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -103218 for 1457 contacts (-70.8/contact) + 2D Compatibility (PS) -20756 + (NN) -2366 + (LL) 5628 1D Compatibility (HY) -10000 + (ID) 2300 Total energy: -133012.0 ( -91.29 by residue) QMean score : 0.441

(partial model without unconserved sides chains): PDB file : Tito_2YYZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2YYZ-query.scw PDB file : Tito_Scwrl_2YYZ.pdb: