Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQFHSSSALITPFKKDLSVDEAAYETLIKRQIFQGMDACVPVGTTGESATLTHKEHMRCIEIAIETCKSTKTPSNSRMKVLAGVGSNATSESLSLAKFAQKIGADAILCVSPYYNRPTQQGLFEHYKTIAQSVEIPVMLYDVPSRTGVSIEVPTALKLFREVPNIKAIKEASGSLKRVTEL-HYYEKDFKIFSGEDSLNHSIMFSGGCGVISVTGNLMPNLISQMVNCALKFEYQQALEIQNKLFDLHQALFVETNPIPIKMAMHLAGLIENPSYRLPLVAPSKETIKLLEKTLQQYEVIA 4DXV Chain:A ((8-291)) -------AIVTPMLKDGGVDWKSLEKLVEWHIEQGTNSIVAVGTTGEASTLSMEEHTQVIKEIIRV-------ANKRIPIIAGTGANSTREAIELTKAAKDLGADAALLVTPYYNKPTQEGLYQHYKAIAEAVELPLILYNVPGRTGVDLSNDTAVRLA-EIPNIVGIKDATGDVPRGKALIDALNGKMAVYSGDDETAWELMLLGADGNISVTANIAPKAMSEVCAVAIAKDEQQAKTLNNKIANLHNILFCESNPIPVKWALHEMGLIDT-GIRLPLTPLAEQYREPLRNALKDAGII-

General information: TITO was launched using: RESULT: Template: 4DXV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -187027 for 2506 contacts (-74.6/contact) + 2D Compatibility (PS) -30958 + (NN) -19458 + (LL) 644 1D Compatibility (HY) -21600 + (ID) 6050 Total energy: -264449.0 ( -105.53 by residue) QMean score : 0.557

(partial model without unconserved sides chains): PDB file : Tito_4DXV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4DXV-query.scw PDB file : Tito_Scwrl_4DXV.pdb: