Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKEMTGLHSLVSIENFIKQHKFSFIYISRPGCTVCHAVLPQLRIVLDQFPNIKLGHINADDVAEVAGRFSVFTVPVLLLFIDGTEFLREARFVHFEQLEQKLKRVYRLYEGE 2OE3 Chain:A ((3-83)) --SITKLTNLTEFRNLIKQNDKLVIDFYATWCGPCKMMQPHLTKLIQAYPDVRFVKCDVDESPDIAKECEVTAMPTFVLGKDG-----------------------------

General information: TITO was launched using: RESULT: Template: 2OE3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 298 -68030 -228.29 -839.87 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -228.29 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.646

(partial model without unconserved sides chains): PDB file : Tito_2OE3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2OE3-query.scw PDB file : Tito_Scwrl_2OE3.pdb: