Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMKKLFHSTLIVLLFFSFFGVQPIHAKKQFKVPNS---VASISKENTYPNASQDQPMLQPSKLAKELLDHSEVKIENPHLIKMLNESNISGTPLAVGYRATIFLGKWALGYESNETVANWEYKKINTNRADNRGGKETAEMHYAQEQQYRVKGGLTAKVPNAEDVKSMMMQKAMKKTNLPLAFETVIGAGTKRDQIYKVAPKKIGYLHAYAPAVNEKGKVTYGEVYLVLKGNKRKLVVKNVTSQGIGAWIPVQDHVTFGFQLSSLPR 4Y8Y Chain:A ((72-123)) ----------------SFFGVQEIIIHDQYKMAESGYDIALLKLETTVGYGDSQRPICLPSKGDRNVI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 4Y8Y.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 57 -1700 -29.82 -34.68 target 2D structure prediction score : 0.24 Monomeric hydrophicity matching model chain A : 0.56 3D Compatibility (PKB) : -29.82 2D Compatibility (Sec. Struct. Predict.) : 0.24 1D Compatibility (Hydrophobicity) : 0.56 QMean score : 0.565

(partial model without unconserved sides chains): PDB file : Tito_4Y8Y.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4Y8Y-query.scw PDB file : Tito_Scwrl_4Y8Y.pdb: