Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNAVIVDAKRTIFGNQNGLLKPFLPEDLAAPIIRCLSRKL---EDQVDEVILGNATGRGG---NLARLSALQAGLPLSVPGMTIDRQCGSGLEAVRYACSLIQAGAGTMYIAGGSESSSQSPFS----ERA---------------RFSPDAI----GDPDMGIAAEYTAARYSISRSMQDEYALLSHQRSRNAHDEGFYREEVVAL----GE----LETDEAFLKTRPIEAIIPRAKPVFDTSSGTVTAANSSGIADGAAALLVMEEEKAAALGLKPVLRFIGSAVSGIHPNFPPAAPVVAIRQLLHTHDVTPDDIDLFEINEAFAVKICVCSQELGIPF--SKINVRGGALALGHPYGASGAALVTRLFYEAKRRPDCQYAVAAIGSGGGIGLALLFEVLA 1ULQ Chain:A ((3-398)) -EAWIVEAVRTPIGKHGGALASVRPDDLLAHALSVLVDRSGVPKEEVEDVYAGCANQAGEDNRNVARMALLLAGFPVEVAGCTVNRLCGSGLEAVAQAARAIWAGEGKVYIGSGVESMSRAPYAVPKPERGFPTGNLVMYDTTLGWRFVNPKMQALYGTESMGETAENLAEMYGIRREEQDRFALLSHQKAVRAWEEGRFQDEVVPVPVKRGKEEILVEQDEGPRRDTSLEKLAA-LRPVF-REGGTVTAGNSSPLNDGAAAVLLVSDDYAKAHGLRPLARVRAIAVAGVPPRIMGIGPVPATRKALERAGLSFSDLGLIELNEAFAAQALAVLREWSLSMEDQRLNPNGGAIALGHPLGASGARILTTLVHEMRRR-KVQFGLATMCIGVGQGIAVVVE---

General information: TITO was launched using: RESULT: Template: 1ULQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2476 -201407 -81.34 -564.16 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.80 3D Compatibility (PKB) : -81.34 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.468

(partial model without unconserved sides chains): PDB file : Tito_1ULQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1ULQ-query.scw PDB file : Tito_Scwrl_1ULQ.pdb: