Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSDNDKFKEELAKLPEVDPMT--KMLVQNIFSKHGVTKDKMKKVSDEEKEMLLNLVKDLQAKSQALIENQKKKKEEAAAQEQKNTKPLSRREQLIEQIRQRRKNDNN 2ZXK Chain:A ((158-211)) ----DSHRQSLLKLPEVNPYVSPSLFVRSAFSP---TASML-KIDAEEEDKLEEILRD-------------------------------------------------

General information: TITO was launched using: RESULT: Template: 2ZXK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 96 -2382 -24.81 -49.61 target 2D structure prediction score : 0.50 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -24.81 2D Compatibility (Sec. Struct. Predict.) : 0.50 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.356

(partial model without unconserved sides chains): PDB file : Tito_2ZXK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2ZXK-query.scw PDB file : Tito_Scwrl_2ZXK.pdb: