Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEHICGTSRIAGFRFSLYPM-TD--DFISVIKSALKKTDTSKVWTKTDHISTVLRGSIDHVFDAAKAIYLHAAN-SEQHIVMNGTFSIGCPGDTQGDTYLSKGDKRVNEDAVRGLKAEAPCQFALYPMNEPDYMGLIMEAVDIAKAQGTFVQGVHYASELDGDAHDVFSTLEAVFRMAEQQTNHITMTVNLSANSPSRKNRKQG 1LXJ Chain:A ((2-88)) ------PKIFCLADVCMVPIGTDSASISDFVALIEKKIRESPLKSTLHSAGTTIEGPWDDVMGLIGEIHEYGHEKGYVRVHTDIRVGTRTDKH---------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 1LXJ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 308 -48801 -158.44 -587.96 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : -158.44 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.419

(partial model without unconserved sides chains): PDB file : Tito_1LXJ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1LXJ-query.scw PDB file : Tito_Scwrl_1LXJ.pdb: