Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAERMVGKQAPRFEMEAVLASKEFGKVSLEENMKNDKWTVLFFYPMDFTFVCPTEITAMSDRYDEFEDLDAEVIGVSTDTIHTHLAWINTDRKENGLGQLKYPLAADTNHEVSREYGVLIEEEGVALRGLFIINPEGELQYQTVFHNNIGRDVDETLRVLQALQT----GGLCPANWKPGQKTL 3QPM Chain:A ((45-225)) LSKAKISKPAPQWEGTAVI-NGEFKELKLSDY--RGKYLVFFFYPLDFTFVCPTEIIAFSDRVHEFRAINTEVVACSVDSQFTHLAWIITPRKQGGLGPMKIPLLSDLTHQISKDYGVYLEDQGHTLRGLFIIDEKGVLRQITMNDLPVGRSVDETLRLVQAFQYTDKHGEVCPAGWKPGSDTI

General information: TITO was launched using: RESULT: Template: 3QPM.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 844 -110751 -131.22 -625.71 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.85 3D Compatibility (PKB) : -131.22 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.85 QMean score : 0.594

(partial model without unconserved sides chains): PDB file : Tito_3QPM.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3QPM-query.scw PDB file : Tito_Scwrl_3QPM.pdb: