Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRILFIGDVVGSPGRDMVKEYVPKLKTKYKPHFTIINGENAAHGKGLTEKIYHSLIQSGADAITMGNHTWDKKEIFDFIDDVPNLVRPANFPEGTPGKGITYVKANGKELAVINLQGRTFLPPLDDPFLKADELIAEAAKRTPYIFIDFHAEATSEKLALGWYTDGRASAVVGTHTHVQTADNRILPKGTAYITDVGMTGPYDGILGMDRETIIKRFKTNLPVRFTVAEGKTTLSGVVIDIDDQTKKAVKIERILINDDHMFFE 2Z06 Chain:B ((1-227)) MRVLFIGDVMAEPGLRAVGLHLPDIRDRYD--LVIANGENAARGKGLDRRSYRLLREAGVDLVSLGNHAWDHKEVYALLESEP-VVRPLNYPPGTPGKGFWRLEVGGESLLFVQVMGRIFMDPLDDPFRALDRLLEE--EKADYVLVEVHAEATSEKMALAHYLDGRASAVLGTHTHVPTLDATRLPKGTLYQTDVGMTGTYHSIIGGEVETFLARFLTGRPQPFRAAQGKA--------------------------------

General information: TITO was launched using: RESULT: Template: 2Z06.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1300 -114001 -87.69 -502.20 target 2D structure prediction score : 0.76 Monomeric hydrophicity matching model chain B : 0.81 3D Compatibility (PKB) : -87.69 2D Compatibility (Sec. Struct. Predict.) : 0.76 1D Compatibility (Hydrophobicity) : 0.81 QMean score : 0.586

(partial model without unconserved sides chains): PDB file : Tito_2Z06.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2Z06-query.scw PDB file : Tito_Scwrl_2Z06.pdb: