Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence METSQEPLVTQKKSKPSVWRSMSLFLVPLLLSNVLQSVGQLVGMMAVGRWLGVDAVAAVSSFFPLFFLLISFTIGIGSGSSILIGQAYGAKNEERLKAVVGTTLTFTFLLGVVLAVIGSIF-TLDILRLMGTPENVIHVSANYARILFYAMPFMFLYFAYTTFLRGTGDSKTPFYTLIVSTVINIALLPVLILGMFGFPKLGIYGSAYATVISTIATFLVLMVYLRKRKHPLQFDKTVRRYLKMDKELLVLLLRLGVPASINMILVSLSEIAVIS-FVNHYGSNATAAYGVVNQVASYVQMPAVSLGIAVSIFAAQSIGANEFDRLKQVIRVGIWLNYIIGGVLIILIYVFSHQILSLFLTEQETLYIAHRLLMITLWSYLLFGNAQIISA-TMRASGTVLWPTVISIF-----AIWGVEVPVAFVLSHYT-----KLEILGVWVGYPAAFAVSLLLIYGYYQFVWKKKQITRLIQ 3MKT Chain:A ((21-450)) ---------------------------PVLIASVAQTGMGFVDTIMAGGVSAID-MAAVSIAASIWLPSILFGVGLLMALVPVVAQLNGAGRQHKIPFEVHQGLILALLVSV--PIIAVLFQTQFIIRFMDVEEAMATKTVGYMHAVIFAVPAYLLFQALRSFTDGMSLTKPAMVIGFIGLLLNIPLNWIFVYGKFGAPELGGVGCGVATAIVYWIMLLLLLFYIVTSKR-LAHVKVFETFHKPQPKELIRLFRLGFPVAAALFF-EVTLFAVVALLVAPLGSTVVAAHQVALNFSSLVFMFPMSIGAAVSIRVGHKLGEQDTKGAAIAANVGLMTGLATACITALLTVLFREQIALLYTENQVVVALAMQLLLFAA-IYQCMDAVQVVAAGSLRG-----YKDMTAIFHRTFISYWVLGLPTGYILGMTNWLTEQPLGAKGFWLGFIIGLSAAALML--GQRLYWLQKQ------

General information: TITO was launched using: RESULT: Template: 3MKT.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2325 -334400 -143.83 -801.92 target 2D structure prediction score : 0.48 Monomeric hydrophicity matching model chain A : 0.74 3D Compatibility (PKB) : -143.83 2D Compatibility (Sec. Struct. Predict.) : 0.48 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.308

(partial model without unconserved sides chains): PDB file : Tito_3MKT.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3MKT-query.scw PDB file : Tito_Scwrl_3MKT.pdb: