Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKILFAVSECTPFVKSGGLADVAGALPKALARLGNEVAVMLPKYSQIPEPWKKRMKKQAECTVAVGWRQQYCGIEHMAENDVNYYFIDNEYYFNRDSLYGHYDDG--ERFAFFSRA-VLEAAKVVNVQA--DIVHTHDWHTAMVNYLLKEEYRKHPFYERMKSVLTIHNLQFQGIFPPDVTHDLLGLEMDHFHYERLECNGFVNFMKAGIIAADHVTTVSPTYRNEIMTPYYGEQLEQVLQYREDDVTGILNGIDDTFYQPKSDPYIEAQYDSGDLACKLENKTKLQQRMGLPEKNDIPLISMVTRLTKQKGLDLVRR---IMHELLEEQDIQLVVLGTGEREFEDYFRYAEFAFHEKCRAYIGFDEPLAHQIYAGSDMFLMPSKFEPCGLGQLIALQYGAIPIVRETGGLYDTVRAYQEEEGTGNGFTFSAFNAHDLKFTIERALSFYCQQDVWK---SIVKTAMNADYSWGKSAKEYQRIFEQVTRSGRDVLE 3L01 Chain:A ((3-427)) MKVLLLGFEFLP-VKVGGLAEALTAISEALASLGHEVLVFTPSHG--------RFQGEEIGKIRVFGEEVQVKVSYEERGNLRIYRIGGGL-LDSEDVYGPGWDGLIRKAVTFGRASVLLLNDLLREEPLPDVVHFHDWHTVFAGALIKK-------YFKIPAVFTIHRLN-KSKLPAFYFHEAGLSELAPYPDIDPEHTG-------GYIA-DIVTTVSRGY----LIDEWG-----FFRNFEGKITYVFNGIDCSFW---NESYLTGSRD--------ERKKSLLSKFGMDEGVTFMFIGRFDR--GQKGVDVLLKAIEILSSKKEFQEMRFIIIGKGDPELEGWARSLEEKHGNVKVITEMLSREFVRELYGSVDFVIIPSYFEPFGLVALEAMCLGAIPIASAVGGLRDIIT-------NETGILVKAGDPGELANAILKALEL-SRSDLSKFRENCKKRAMS--FSWEKSAERYVKAY------------

General information: TITO was launched using: RESULT: Template: 3L01.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2391 -82854 -34.65 -200.13 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -34.65 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.448

(partial model without unconserved sides chains): PDB file : Tito_3L01.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3L01-query.scw PDB file : Tito_Scwrl_3L01.pdb: