Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLM-----QDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWP---EVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM 2B9H Chain:A ((11-313)) -SDFQLKSLLGEGAYGVVCSATHKPTGEIVAIKKIEPFD-KPLFALRTLREIKILKHFKHENIITIFNIQRPDSFENFNEVYIIQELMQTDLHRVIST----QMLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLARIID------VEFVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIGTPHSDNDLRCIESPRAREYIKSLPMYPAAPLEKMFPRVNPKGIDLLQRMLVFDPAKRITAKEALEHPYLQTYHDPNDEP

General information: TITO was launched using: RESULT: Template: 2B9H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -153798 for 2175 contacts (-70.7/contact) + 2D Compatibility (PS) -29160 + (NN) -10630 + (LL) 716 1D Compatibility (HY) -28800 + (ID) 5300 Total energy: -226972.0 ( -104.35 by residue) QMean score : 0.504

(partial model without unconserved sides chains): PDB file : Tito_2B9H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2B9H-query.scw PDB file : Tito_Scwrl_2B9H.pdb: