Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYV--TFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF 3NIZ Chain:A ((19-308)) -------LMEKYQKLEKVGEGTYGVVYKAKD-SQGRIVALKRIR---------GIPSTAIREISLLKELHHPNIVSLIDVIHSERCLTLVFEFMEKDLKKVLDENKTGLQDSQIKIYLYQLLRGVAHCHQHRILHRDLKPQNLLINSDGALKLADFGLARAFGIPVR---HEVVTLWYRAPDVLMGSKKYSTSVDIWSIGCIFAEMITGKPLFPGVTDDDQLPKIFSILGTPNPREWPQVQELPLWKQRTFQVFEKKPWSSIIPGFCQEGIDLLSNMLCFDPNKRISARDAMNHPYFKDLDPQI--------------------------------------------

General information: TITO was launched using: RESULT: Template: 3NIZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -183197 for 2186 contacts (-83.8/contact) + 2D Compatibility (PS) -29607 + (NN) -13883 + (LL) 2904 1D Compatibility (HY) -29200 + (ID) 6450 Total energy: -259433.0 ( -118.68 by residue) QMean score : 0.535

(partial model without unconserved sides chains): PDB file : Tito_3NIZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3NIZ-query.scw PDB file : Tito_Scwrl_3NIZ.pdb: