Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQSKRGRPRDEGTHKAILSAAYDLLLEKGFDAVTVDKIAERAKVSKATIYKWWSNKAAVIMDSFLSTATDRL-PVPDTGSSVQDIVTHATNLARFLTS-REGTVIKELIGAGQLDEKLAEEYRTRFFQPRRLQAKGLLEKGIQKGELRENLDIEVSIDLIYGPIFYRLLITGDEV-NDSYVRDLVMNAFKGVQATSATESM 4JKZ Chain:A ((11-188)) ---------SEKSRVAIVEATRALLLERGFDGLSIEAVAAKAGVGKQTIYRWWPSRHALVADVLLEDADKILARMPKTDDVTADLASWAGTLAAALTTRRGHAMLKTLMAASLEHEDTAARL----REGFSRPLIESVRDRLRDEDIDAD-HAQAAADALLGAVVNAVLSEGRSYSR-QRAETSARIIVAGLR--------

General information: TITO was launched using: RESULT: Template: 4JKZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 684 -93273 -136.36 -532.99 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : -136.36 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.552

(partial model without unconserved sides chains): PDB file : Tito_4JKZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4JKZ-query.scw PDB file : Tito_Scwrl_4JKZ.pdb: