Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKWNPLIPFLLIAVLGIGLTFFLSVKGLDDSREIASGGESKSAEKKDANASPEEIYKANCIACHGENYEG--VSGPSLKGVGD-----------------------KKDVAEIKTKIEKGGN-------------GMPSG-LVPADKLDDMAEWVSKIK 3C2C Chain:A ((3-112)) -----------------------------------------------DAAAGEKVS-KKCLACHTFDQGGANKVGPNLFGVFENTAAHKDNYAYSESYTEMKAKGLTWTEANLAAYVKNPKAFVLEKSGDPKAKSKMT-FKLTKDDEIENVIAYLKTLK

General information: TITO was launched using: RESULT: Template: 3C2C.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 172 10091 58.67 142.13 target 2D structure prediction score : 0.82 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : 58.67 2D Compatibility (Sec. Struct. Predict.) : 0.82 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.464

(partial model without unconserved sides chains): PDB file : Tito_3C2C.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3C2C-query.scw PDB file : Tito_Scwrl_3C2C.pdb: